High- vs. Standard-Dose Heparin for Radial Artery Catheterization

A lower rate of radial artery occlusion was seen with high-dose heparin in diagnostic coronary angiography.

Radial artery catheterization is gaining popularity and use among interventionalists due to increasing familiarity, less risk for retroperitoneal bleeding than with transfemoral approaches, and patient preference. However, radial artery occlusion (RAO), usually asymptomatic, occurs in up to 10% of patients. In a randomized study to determine optimal heparin dosing, investigators compared standard-dose (50 IU/kg) with high-dose (100 IU/kg) heparin in 3102 patients undergoing radial artery catheterization for diagnostic coronary angiography in Greece (NCT02570243).

Baseline characteristics were similar in the two groups except that the standard-dose group was slightly more obese and had a lower incidence of abnormal Allen tests. Vascular ultra…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)