Intervention Options for Uncontrolled Peptic Ulcer Bleeding After Endoscopic Therapy

Compared with surgery, transarterial embolization was associated with decreased mortality, length of stay, and complications but increased rebleeding risk.

When mainstay endoscopic therapy fails to treat bleeding peptic ulcers or rebleeding occurs, surgery has been the traditional next-step therapy; however, transarterial embolization (TAE) performed by interventional radiologists is increasingly utilized. Comparative studies of these therapies to date are limited by small size and single-center design.

In a population-based, retrospective cohort study in Stockholm, Sweden, researchers compared outcomes between 97 patients who underwent TAE and 185 who underwent surgery for refractory peptic ulcer bleeding after endoscopic therapy.

During a median follow-up of approximately 3 years, the overall risk for death was 34% lower in the TAE group (adjusted hazard ratio, 0.66). In addition, the TAE grou…

Reviewing Author

John R. Saltzman, MD

Disclosures

Consultant/Advisory BoardIterative Scopes

Editorial BoardsGastrointestinal Endoscopy; UpToDate

Leadership Positions in Professional SocietiesAmerican College of Gastroenterology (Trustee)

OtherVice President of Medical Affairs, 1Globe Health Institute