A Little Pudgy, but Better Survival in Sepsis?

In a retrospective cohort of more than 55,000 individuals with sepsis, survival directly correlated with body-mass index.

Previous investigations have indicated that, counterintuitively, obesity might be associated with better outcomes in sepsis. Researchers have now tested this hypothesis with data from a large national database comprising more than 2.5 million admissions to 139 U.S. hospitals between 2009 and 2015 and including more than 138,000 sepsis encounters.

Some 55,000 patients with a diagnosis of sepsis according to Sepsis 3.0 criteria and with documented body-mass indices (BMI) were further evaluated. Patients were classified as underweight (BMI <18.5 kg/m²), normal weight (18.5–24.9 kg/m²), overweight (25.0–29.9 kg/m²), obese class I (30.0–34.9 kg/m²), obese class II (35.0–39.9 kg/m²), and morbidly obese (class III, ≥40 kg/m²). Unadjusted in-hospita…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

A Little Pudgy, but Better Survival in Sepsis?

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Reviewing Author