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Randomized studies assessing diagnostic test efficacy are performed less frequently than assessments of interventions, and they rarely demonstrate patient benefit (J Clin Epidemiol 2017; 84:61).
To determine the effects of prehospital arterial blood gas (ABG) analysis on diagnostic accuracy and whether ABG analysis informed subsequent therapeutic interventions, investigators randomized critically ill patients with Glasgow Coma Scores <13 being treated on an anesthesiologist-staffed mobile care unit to standard care with or without ABG analysis. “Diagnostic accuracy” was defined as the proportion of patients assigned a specific ICD-10 code by the prehospital physician (expected percentage, 96.0%; aim, increase to 96.4%).
In all, 222 patients h…