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Neonatal herpes simplex virus (HSV) infection is rare but results in significant morbidity and mortality, even despite treatment. In the current retrospective study, investigators examined recent trends in incidence, mortality, and healthcare burden in the U.S.
From a Medicaid population of over 2 million births between 2009 and 2015, researchers identified 900 infants with neonatal HSV infection diagnosed during a hospitalization admission. Outcomes were mortality during the index hospitalization and subsequent healthcare utilization during the 6 months after index hospitalization. Findings include the following:
Disease incidence increased significantly during the study period: from 3.4 per 10,000 in 2009 to 5.3 per 10,000 in 2015, averagin…