Scheduled vs. On-Demand Dilation of Dominant Strictures in Primary Sclerosing Cholangitis

Long-term outcomes were better with scheduled endoscopic surveillance and dilation of dominant strictures.

Many patients with primary sclerosing cholangitis (PSC) develop dominant strictures (DS) that often warrant aggressive interventions such as dilation and stenting via endoscopic retrograde cholangiopancreatography (ERCP). In a retrospective study, investigators compared outcomes between patients receiving scheduled versus on-demand dilation of DS over a 30-year period in Germany.

Patients were offered scheduled endoscopic dilation of DS or on-demand dilation of DS based on clinical symptoms, episodes of cholangitis, laboratory values, etc. The scheduled protocol comprised an annual ERCP and, when DS were found, repeat procedures at 4 weeks, 3 months, and then every 6 months until stricture resolution, followed by yearly ERCP thereafter. Medi…

Reviewing Author

Douglas G. Adler, MD, FACG, AGAF, FASGE

Disclosures

Consultant/Advisory BoardBSC; Merit; Olympus

Speaker’s BureauAbbVie

Editorial BoardsGastrointestinal Endoscopy

Douglas G. Adler, MD, FACG, AGAF, FASGE

Disclosures

Consultant/Advisory BoardBSC; Merit; Olympus

Speaker’s BureauAbbVie

Editorial BoardsGastrointestinal Endoscopy

Scheduled vs. On-Demand Dilation of Dominant Strictures in Primary Sclerosing Cholangitis

Topics

Reviewing Author