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Chronic traumatic encephalopathy (CTE) is a tau-related neurodegenerative process with minimal amyloid deposition found in people with repetitive head impacts. Clinically, both cognitive and neuropsychiatric symptoms can occur. To determine whether tau and amyloid deposition can be identified during life in patients diagnosed with CTE, researchers used flortaucipir positron-emission tomography (PET) to identify any tau-related changes and florbetapir PET to identify any amyloid deposition in 26 former National Football League (NFL) players with cognitive and neuropsychiatric symptoms and in 31 controls without histories of traumatic brain injury. In this manufacturer-funded study, participants also underwent screening mental status exam, ne…