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Epidemiologic data from the United States show rising colorectal cancer (CRC) incidence in individuals younger than 50. Two studies report the epidemiology of young-onset CRC in other countries.
In one study, investigators assessed CRC incidence and mortality in about 144 million people aged 20 to 49 years from 20 European countries. In individuals aged 20 to 29, CRC incidence increased from 0.8 to 2.3 cases per 100,000 persons between 1990 and 2016. The increase accelerated from 1.7% (1990–2004) to 8% per year (2004–2016). There were similar trends in older age groups, but the annual increases between 2004 and 2016 were less marked (5% for 30- to 39-year-olds and 1.6% for and 40- to 49-year-olds). Overall, colon cancer incidence rose more t…