Do Young Infants with Urinary Tract Infection Need Lumbar Puncture?

A meta-analysis examines the risk for meningitis in infants aged 29 to 90 days with UTI.

Investigators conducted a systematic review and meta-analysis to identify the prevalence of bacterial meningitis in infants aged 29 to 90 days who have abnormal urinalysis or urine culture and have undergone lumbar puncture (LP). The well-structured search yielded 20 studies (3 prospective, 17 retrospective) that were subject to a robust statistical analysis of the pooled data.

Among a total of 3868 infants, they identified 11 cases of bacterial meningitis. Random effects modeling of pooled data demonstrated a prevalence of 0.25% (confidence interval 0.09%–0.7%) for bacterial meningitis in infants with urinary tract infection (UTI). Previous studies demonstrated a meningitis prevalence of 0.2% to 0.3% in the same age group; it therefore appe…

Reviewing Author

Carolyn K. Holland, MD, MEd, FACEP, FAAP

Disclosures

EquityGeneral Electric

Leadership Positions in Professional SocietiesSociety for Academic Emergency Medicine (Program Committee Chief Resident Forum Subcommittee Chair); American College of Emergency Physicians (Education Committee member)

Carolyn K. Holland, MD, MEd, FACEP, FAAP

Disclosures

EquityGeneral Electric

Do Young Infants with Urinary Tract Infection Need Lumbar Puncture?

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Reviewing Author