A randomized trial shows effectiveness of regular assisted standing when done frequently at home.
Investigators randomized 71 patients with progressive multiple sclerosis (MS) to a home standing frame group and 69 patients to usual-care group. The home standing frame consists of platforms with adjustable, padded bars to support the legs and torso. Participants were instructed to stand in the frame for 30 minutes, three times per week. After 20 weeks, they were encouraged to continue on their own volition. At baseline, patients required a walker to ambulate, or they were nonambulatory.
In each group, 61 participants completed the 36-week study. At 36 weeks, motor function (measured by the Amended Motor Club Assessment score) was a baseline-adjusted 4.7 points higher in the standing frame group. As anticipated, scores were even higher when…
Reviewing Author
DisclosuresConsultant/Advisory BoardAlexion Pharmaceuticals; Amgen; Astoria; Biogen; Bristol Myers Squibb; Celltrion; Genentech; Hoffmann-La Roche; Genzyme; EMD Serono; Immpact-Bio; Immunic Therapeutics; Kyverna; Lundbeck; Novartis; Sandoz; TG Therapeutics
Grant/Research SupportNational Institutes of Health; National Multiple Sclerosis Society; U.S. Department of Defense
Leadership Positions in Professional SocietiesConsortium of Multiple Sclerosis Centers (Treasurer)
DisclosuresConsultant/Advisory BoardAlexion Pharmaceuticals; Amgen; Astoria; Biogen; Bristol Myers Squibb; Celltrion; Genentech; Hoffmann-La Roche; Genzyme; EMD Serono; Immpact-Bio; Immunic Therapeutics; Kyverna; Lundbeck; Novartis; Sandoz; TG Therapeutics
Grant/Research SupportNational Institutes of Health; National Multiple Sclerosis Society; U.S. Department of Defense
Leadership Positions in Professional SocietiesConsortium of Multiple Sclerosis Centers (Treasurer)