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The need to return to the operating room for positive margins after breast-conserving surgery delays adjuvant therapy, is upsetting to patients, and is expensive for individuals and health systems. Prior, single-center studies have shown that circumferential resection of additional tissue around the tumor cavity (cavity shave margin [CSM]) reduces the rate of positive margins and re-excision in breast cancer patients undergoing partial mastectomy (PM).
To further assess the benefit of CSM resection in this setting, investigators conducted a multicenter, randomized trial in which 400 stage 0–III breast cancer patients undergoing PM were assigned to either have CSM resection (shave group) or not have CSM resection (no shave group). Randomizati…