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Endoscopic ultrasound–guided liver biopsy (EUS-LB) is a technique still in development. Tools and techniques, which lobe to sample, and other questions inspire considerable debate. A recent prospective, randomized study compared the use of fine-needle aspiration (FNA) needles with fine-needle biopsy (FNB) needles for EUS-LB.
The authors randomized 40 patients to EUS-LB with either a 19-gauge (19G) FNA or 19G FNB needle and evaluated multiple parameters relevant to liver biopsy specimens. Bilobar samples were obtained from all patients. Specimens were evaluated both pre- and postprocessing. The primary outcome was length of the longest piece of liver core specimen. The mean preprocessing length of the longest specimen piece was 2.09 cm (stand…