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Patients with advanced knee osteoarthritis that is isolated to a single compartment (medial tibiofemoral, lateral tibiofemoral, or patellofemoral) are potential candidates for partial, unicompartmental knee arthroplasty (PKA) or total knee arthroplasty (TKA). However, observational data suggest that patients who undergo PKA are at higher risk for early revision than those who undergo TKA (NEJM JW Gen Med May 1 2019 and BMJ 2019; 364:352). In this trial from the U.K., 528 patients with isolated medial-compartment osteoarthritis — all of whom were considered to be suitable for PKA according to standard criteria — were randomized to PKA or TKA.
At 5 years, standardized knee scores (assessing function and pain) were similar in the two groups, bu…