Does Endometriosis Increase Risk for Certain Adverse Pregnancy Outcomes?

A large prospective cohort study suggests endometriosis is associated with adverse outcomes, including early pregnancy loss.

Although endometriosis is associated with infertility, most women with this disorder do eventually achieve pregnancy. But is endometriosis also associated with adverse pregnancy outcomes? To address this question, investigators utilized data from women participating in the prospective cohort Nurses' Health Study II from 1989 through 2009 (age range at study entry, 25–42).

A total of 8875 pregnancies in women with laparoscopically confirmed self-reported endometriosis were included. In analysis accounting for multiple pregnancies per woman, pregnancies in women with a history of endometriosis had higher relative risk for spontaneous abortion (RR, 1.40) and ectopic pregnancy (RR, 1.46) compared with 187,847 pregnancies without any history of e…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Does Endometriosis Increase Risk for Certain Adverse Pregnancy Outcomes?

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Reviewing Author