Loading...
Researchers explored previous conflicting findings about a relation between alcohol intake and development of dementia by performing secondary analyses of a prior large prospective dementia clinical trial (JAMA 2008; 300:2253). Alcohol consumption patterns and baseline cognition of 3021 participants (median age, 78; mostly white) were assessed at baseline. Cognitive function was assessed every 6 months during a median follow-up of 6 years.
Analyses were adjusted for a wide range of clinical and demographic factors. The association of alcohol intake with incident dementia depended on baseline cognition, as follows:
For patients without baseline mild cognitive impairment (MCI), no level of alcohol consumption was associated with any excess risk…