Among other findings, AIDS-defining opportunistic infections decreased from 79% in 1984–1987 to 29% in 2012–2016, while nonopportunistic infections increased from 37% to 57% in the same time period.
Autopsy findings are critical in identifying causes of death, yet the number of autopsies done in the U.S. continues to decline. In this retrospective study, investigators examined trends in autopsy findings among 286 persons who died with HIV/AIDS at a single hospital in New York City from 1984 through 2016.
After excluding autopsies done on 7 fetuses and 27 children younger than 7 years, a total of 252 cases (86% male) were analyzed: 157 in the pre–highly active antiretroviral therapy (HAART) era (1984–1995), with an average of 13 autopsies per year, and 89 post-HAART (1997–2016), with an average of 4.5 autopsies per year. Mean age at death was 35±7 years in 1984 and increased to 54±7 years in 2010, trending downward after that. Mean CD4+ …
Reviewing Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)