Simple or Radical Hysterectomy for Early-Stage Cervical Cancer?

For microscopic cervical cancer, both approaches had similar long-term outcomes; for stage IB1 disease, radical hysterectomy had superior long-term survival.

How effective is conservative surgery for early-stage cervical cancer? In this observational study, investigators queried the National Cancer Database (2004–2015) to study the outcomes of cervical cancer stage IA2 (microscopic tumors) and IB1 (tumors <2 cm in diameter) managed with simple or radical hysterectomy. Radical hysterectomy, which involves resection of the uterus along with surrounding parametria, upper vagina, and uterosacral ligaments, typically is performed by gynecologic oncologists.

Among 1530 women with stage IA2 and 3931 women with stage IB1 cervical cancer, 45% and 35%, respectively, had a simple hysterectomy. Propensity score weighting was used to assess 5-year survival. Among women with stage IA2 cervical cancer, the 5-ye…

Reviewing Author

Robert L. Barbieri, MD

Disclosures

Grant/Research SupportNational Institutes of Health

Editorial BoardsUpToDate

Robert L. Barbieri, MD

Disclosures

Grant/Research SupportNational Institutes of Health

Editorial BoardsUpToDate

Simple or Radical Hysterectomy for Early-Stage Cervical Cancer?

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Reviewing Author