Risk for Systemic Artery Aneurysm in Children with Kawasaki Disease

These lesions are uncommon, but screening for them may be indicated in high-risk patients.

In Kawasaki disease (KD), coronary artery aneurysm (CAA) is the most commonly recognized complication. The incidence of systemic artery aneurysm (SAA) is less well known, as screening requires extensive diagnostic techniques (full-body magnetic resonance angiography [MRA] or peripheral angiography [PA]).

Investigators at a children's hospital in China prospectively examined short-term outcomes in 1148 children with KD. Within 2 months of KD onset, those at high risk for developing SAA (having giant CAA, progression of CAA during treatment, or KD unresponsive to 2 doses of IVIG) were screened with MRA, and children undergoing coronary angiography (for medium or giant CAA) underwent simultaneous PA. Findings were as follows:

CAAs were detected …

Reviewing Author

Deborah Lehman, MD

Disclosures

Nothing to disclose

Deborah Lehman, MD

Disclosures

Nothing to disclose

Risk for Systemic Artery Aneurysm in Children with Kawasaki Disease

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Reviewing Author