Balloon-Expandable TAVR Beats Self-Expanding TAVR

Propensity-matched comparisons from two French registries demonstrated lower mortality with the balloon-expandable devices.

No large randomized head-to-head comparisons of the two dominant transcatheter aortic valve replacement (TAVR) prostheses have been performed. Now, investigators have used propensity analysis to compare them in patients in two French registries.

The first study included 12,804 patients in the FRANCE-TAVI registry (NCT01777828) between 2013 and 2015; propensity-score-matched cohorts of 3910 pairs of balloon-expandable (BE) and self-expanding (SE) procedures were compared. Moderate or greater paravalvular regurgitation (PVR) at discharge occurred more frequently with SE than BE valves (15.5% vs. 8.3%; relative risk, 1.90). In-hospital mortality was also higher in patients receiving SE valves (5.6% vs. 4.2%; RR, 1.33). The need for a new pacema…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)