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Intra-abdominal infections range from localized processes to diffuse peritonitis and are caused by various pathogens occurring in diverse clinical settings. Researchers conducted an observational epidemiological study of this heterogeneous disease in 2621 critically ill adults with intra-abdominal infections at 309 international centers between January and December 2016. Of the infections, 32% were community-acquired, while 68% were hospital-acquired (early-onset in 25.0%, and late-onset in 43%). Organ failure and septic shock were more frequent with hospital-acquired infection.
Secondary peritonitis composed 68% of cases, followed by biliary tract infections, intra-abdominal abscesses, and peripancreatic infections (12%, 7%, and 6%, respect…