Primary Care Prescribing Practices in Children with Chronic Kidney Disease

In a U.K. study, over 25% of children with CKD received a well-established nephrotoxic medication during a 3-year period.

Children with chronic kidney disease (CKD) receive most of their healthcare in primary care settings. To assess their exposure to potentially nephrotoxic medications in these settings, researchers conducted a retrospective cohort study using population-based data from primary care practices in the U.K.

Participants were 1018 children with incident CKD and a matched cohort of 4072 children without CKD. Medications were categorized into well-established nephrotoxins (group A) and a broader group of potentially nephrotoxic medications inclusive of group A (group B).

During a mean follow-up of 3.3 years, 26% of children with CKD and 15% of those without kidney disease received a group A medication. Nonsteroidal anti-inflammatory drugs (NSAIDs) we…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Primary Care Prescribing Practices in Children with Chronic Kidney Disease

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Reviewing Author