Behavioral Therapy Is More Effective than Drug Therapy for Overactive Bladder Symptoms in Men

Management of overactive bladder (OAB) symptoms in men generally is limited to drug therapies (e.g., α-adrenergic receptor antagonists, antimuscarinic agents). However, in women, combined therapy (behavioral plus drug therapies) is more effective than drug therapy alone. To evaluate the effectiveness of combined therapy in men, researchers conducted a multisite study in more than 200 men (mean age, 64) with OAB symptoms (baseline mean voids/24 hours, 12; baseline nocturia, 2.1). Participants were randomized to one of three groups:

• Drug therapy alone: tolterodine (4 mg/daily) plus tamsulosin (0.4 mg/daily)

• Behavioral therapy alone: Three clinic visits focused on pelvic floor muscle and urge suppression training plus contraction-relaxation exer…