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Across various psychiatric disorders, investigations using functional MRI (fMRI) have revealed neural circuit disruptions, largely within networks involving cognitive control and emotional processing. However, fMRI is expensive and has limited clinical applications, thus stimulating interest in less-expensive neuroimaging modalities like electroencephalography (EEG). Traditional EEG techniques, however, measure summed electrical voltages at the scalp, which results in “signal smearing,” reflecting countless jumbled brain processes and volume conduction problems. In a two-part study, investigators tried a new approach.
First, the investigators developed new EEG analytic methods (yielding “power envelopes” based on mathematical correlations of…