Recommendations for the Care of Children with Williams Syndrome

The American Academy of Pediatrics consensus report offers recommendations for monitoring and managing major and minor manifestations of Williams syndrome.

Williams syndrome (WS), a genetic condition occurring in 1 of 7500 children, is a multisystem disorder that requires care from both primary care and specialist pediatricians. An American Academy of Pediatrics expert panel has published a clinical report to guide pediatricians in caring for patients with WS.

Among the recommendations:

Cardiovascular disorders (most often supravalvular aortic stenosis) occur in more than 80% of patients. Hypertension is present in 50% of patients and may be due to renal artery stenosis. Children with WS are at risk for sudden death. Consultation with a pediatric cardiologist and possibly a nephrologist is indicated for all children with WS.
Pediatric neurology consultation should be pursued for evaluation of and…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Recommendations for the Care of Children with Williams Syndrome

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Reviewing Author