Recurrence of Venous Thromboembolism in the Context of Metabolic Syndrome

VTE recurrence increased with the number of metabolic syndrome components.

Whether or not to extend anticoagulation for venous thromboembolism (VTE) after 3 months of therapy depends on the continued presence of risk factors for recurrence, including uncontrolled medical illnesses.

To test the hypothesis that components of metabolic syndrome (hyperlipidemia, obesity, hypertension, and diabetes) impact VTE recurrence, investigators retrospectively measured the prevalence of metabolic syndrome in 151,000 patients with deep venous thrombosis (DVT; mean age, 58 years) in the Indiana Network for Patient Care from 2004 to 2017. Of these patients, 68% had at least one component of metabolic syndrome; hypertension was the most common component and was present in 58%.

Key results were as follows:

VTE recurrence over 2 years i…

Reviewing Author

Brady L. Stein, MD, MHS

Disclosures

Leadership Positions in Professional SocietiesAmerican Society of Hematology (Senior Editor, ASH Self-Assessment Program; guideline development)

Brady L. Stein, MD, MHS

Disclosures

Leadership Positions in Professional SocietiesAmerican Society of Hematology (Senior Editor, ASH Self-Assessment Program; guideline development)

Recurrence of Venous Thromboembolism in the Context of Metabolic Syndrome

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Reviewing Author