Poor Inter-Reader Reliability of Magnetic Resonance Cholangiopancreatography in Primary Sclerosing Cholangitis

Patients with primary sclerosing cholangitis (PSC) often undergo surveillance via magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP). MRCP findings are used to determine which patients should undergo endoscopic retrograde cholangiopancreatography (ERCP) and which maneuvers are to be performed during the ERCP. Investigators of a recent study aimed to assess inter-reader agreement on interpretation of MRCP in patients with PSC.

A total of 40 patients with large-duct PSC underwent surveillance MRI with MRCP at two time points. Two imaging sets per patient, with and without 3D reconstructions, were independently evaluated by two radiologists for bile duct changes during separate reading sessions. When compar…