MRI-Targeted and Systematic Biopsy for Prostate Cancer Diagnosis

More cancers were diagnosed by using both techniques than by using either one alone.

For the past several decades, transrectal, ultrasonographically guided, 12-core systematic biopsy has been the most widely applied technique for the initial diagnosis and grading of prostate cancer. However, this approach is associated with missed diagnoses and grade misclassifications. Prior research has shown that multiparametric MRI-targeted biopsy identifies clinically significant prostate cancers more accurately than conventional systematic biopsy in men with suspected localized prostate cancer (NEJM JW Gen Med Apr 15 2018 and N Engl J Med 2018; 378:1767).

To further evaluate the two techniques, individually and in combination, investigators at the NIH conducted a prospective trial (Trio) in which 2013 treatment-naive men with an elevat…

Reviewing Author

Robert Dreicer, MD, MS, MACP, FASCO

Disclosures

Consultant/Advisory BoardAstellas; Aveo; Bayer; Gilead; Merck; Pfizer; Propella; Macrogenics

Editorial BoardsCurrent Urology Reports

Robert Dreicer, MD, MS, MACP, FASCO

Disclosures

Consultant/Advisory BoardAstellas; Aveo; Bayer; Gilead; Merck; Pfizer; Propella; Macrogenics

Editorial BoardsCurrent Urology Reports

MRI-Targeted and Systematic Biopsy for Prostate Cancer Diagnosis

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Reviewing Author