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Postpartum psychosis denotes a severe mood disorder episode having psychotic, manic, or mixed affective symptoms and occurring within the first few weeks after childbirth. As new mothers and families facing this diagnosis need information on long-term prognosis, researchers conducted a review and meta-analysis covering six studies (mean follow-up in 645 of 954 patients with an index episode of postpartum psychosis, 16 years).
Overall, 36% of women had no further psychotic episodes; among the remainder (64%) who did have a subsequent episode, the majority (57%) experienced it outside the postpartum period. Among 336 women with a subsequent pregnancy, 27% had another episode associated with that pregnancy. In two studies, 66% of participants h…