Loading...
Nearly 3% of reproductive-aged U.S. women have type 1 or type 2 diabetes and 6% of pregnancies are complicated by gestational diabetes. In addition, diabetes diagnosed before pregnancy (pregestational diabetes) is a well-known risk factor for poor pregnancy outcomes, including birth defects. Assessing risk for individual birth defects related to diabetes has been challenging because of the low incidence of specific anomalies. Therefore, investigators examined data on 31,000 pregnancies affected by 50 distinct fetal anomalies in the National Birth Defects Prevention Study (NBDPS) from 1997 through 2011 to assess more accurately the association of an isolated defect with pregestational or gestational diabetes.
Statistically significant associa…