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Cognitive-behavioral therapy (CBT) is frequently helpful for depressed patients with Parkinson disease, but access to services can be difficult. To learn about the efficacy of a 10-session, telephone-delivered CBT intervention (weekly for 3 months and then monthly for another 6 months), researchers randomized 72 patients with Parkinson disease and depression diagnoses to the CBT intervention plus medical and psychiatric treatment as usual (TAU) or to TAU alone.
Telephone CBT+TAU was shown to be better than TAU alone on all depression, anxiety, and quality-of-life measures. On the Hamilton Depression Rating Scale (the primary outcome measure), participants improved 6.53 points with telephone CBT+TAU versus a worsening of 0.27 points with TAU …