Colonoscopy vs. Fecal Immunochemical Test vs. Risk-Stratified Screening

Baseline results are promising for a risk-stratified approach.

There are several strategies for colorectal cancer (CRC) screening in the opportunistic setting (NEJM JW Gastroenterol Aug 2017 and Am J Gastroenterol 2017; 112:1016). Risk-stratified approaches use CRC risk factors to guide patients to colonoscopy or less-invasive options according to predicted neoplasia risk. Several scoring systems are available but are not widely used, and the effectiveness of risk-based screening is not known.

To address this knowledge gap, investigators initiated a multicenter, randomized, controlled trial (RCT) in China comparing colonoscopy, fecal immunochemical testing (FIT), and risk-stratified screening using the Asia Pacific Colorectal Screening (APCS) score. APCS includes five risk factors for CRC: age, sex, fam…

Reviewing Author

Charles J. Kahi, MD, MS

Disclosures

Grant/Research SupportU.S. Department of Veterans Affairs (VA) HSR&D; VA Cooperative Studies Program; VA QUERI

Editorial BoardsClinical Gastroenterology and Hepatology; AGA Perspectives

Charles J. Kahi, MD, MS

Disclosures

Grant/Research SupportU.S. Department of Veterans Affairs (VA) HSR&D; VA Cooperative Studies Program; VA QUERI

Editorial BoardsClinical Gastroenterology and Hepatology; AGA Perspectives

Colonoscopy vs. Fecal Immunochemical Test vs. Risk-Stratified Screening

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Reviewing Author