What Does Hypertension During DKA Mean for Fluid Management?

Not as much as we might assume

Diabetic ketoacidosis (DKA) is often associated with significant dehydration, and the presence of hypertension may confuse the fluid resuscitation strategy. The current study is a secondary analysis of randomized, controlled trial data in 1258 children (age, 0–18 years) admitted to the hospital for treatment of DKA. Researchers examined clinical and hemodynamic measures before and after rapid or slow rehydration and relationships between these measures and incidence of hypertension. Results were as follows:

Average heart rate was three standard deviations above the age- and sex-adjusted mean on admission.
Average systolic and diastolic blood pressures were also elevated by 1 standard deviation on admission.
Hypertension was present in 12% of c…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

What Does Hypertension During DKA Mean for Fluid Management?

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Reviewing Author