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Several observational studies suggest that hospitalized patients with COVID-19 may be at heightened risk for thromboembolic complications. Two recent studies from several centers in Wuhan, China, support this hypothesis.
Zhang and colleagues reported on 143 consecutive patients with COVID-19 (mean age, 63; 48% women) who were hospitalized from January 29 to February 29, 2020, at a single academic center and who underwent lower-extremity venous ultrasound scanning. Almost half of the patients (46%) developed a lower-extremity deep venous thrombosis (DVT). Patients who had a DVT were on average older than patients without DVT, were more likely to have adverse clinical events, and had higher mortality (34.8% vs. 11.7%). Combining a CURB-65 scor…