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Current guidelines recommend consideration of endovascular thrombectomy (EVT) for acute ischemic stroke only when the clinical deficit measured by the NIH stroke scale is >5. The role of EVT is unclear in patients with milder clinical deficits, especially in the presence of a large vessel occlusion, such as in the distal internal carotid or middle cerebral artery.
In a multicenter retrospective study, researchers compared outcomes in patients with minor stroke (NIH stroke scale ≤5) and presence of a large vessel occlusion who received intended therapy with intravenous thrombolysis (IVT; alteplase) alone or with adjunctive EVT. Propensity-score weighting was used to account for baseline differences. A modified Rankin Scale score of 0 to 1 at …