Benign Nature of Asymptomatic Intracranial Arterial Stenosis

Asymptomatic intracranial stenosis increased with age but was not associated with recurrent stroke risk in patients with minor cerebrovascular events.

Whereas symptomatic intracranial stenosis is associated with increased recurrent-stroke risk, less information is available on the prognosis of asymptomatic intracranial stenosis (ICS). To gain insight, investigators conducted a population-based assessment (Oxford Vascular Study) in the U.K. among patients with transient ischemic attack (TIA) or minor stroke recruited during a 7-year period. All patients received intensive medical therapy, including dual antiplatelet therapy for 1 month (followed by monotherapy), high-potency statins, and blood pressure treatment to current targets. The primary study goals were determining the prevalence of asymptomatic ICS and the prognosis of patients with asymptomatic ICS.

A total of 1368 patients (mean a…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Benign Nature of Asymptomatic Intracranial Arterial Stenosis

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Reviewing Author