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Tourette syndrome (TS) is a neuropsychiatric disorder marked by involuntary tics, often associated with premonitory urges. Current treatments, including medications and psychological interventions, are often inadequate. Prior studies in TS patients have shown abnormalities in electroencephalographic signals in alpha or mu bands associated with sensorimotor function before tic execution and also that noninvasive brain stimulation can entrain brain oscillations and reduce tics. On the basis of these observations, investigators examined whether peripheral median nerve stimulation (MNS) might entrain specific mu oscillations linked to motor suppression and affect tic production.
They demonstrated that in healthy adults, rhythmic, but not arrhyth…