Effectiveness of Hemostatic Spray to Treat Bleeding Peptic Ulcers

In a multicenter international registry, use of a hemostatic spray achieved excellent hemostasis rates.

Upper gastrointestinal bleeding due to actively bleeding peptic ulcers represents an endoscopic treatment challenge. Despite our current combination endoscopic therapies, further bleeding may occur and is associated with significant morbidity and mortality. Hemostatic sprays can stop active bleeding in the gastrointestinal tract; however, the real-world effectiveness of this treatment is unknown.

Using prospectively collected data from a multicenter international registry, researchers examined outcomes in 202 patients with bleeding ulcers treated with TC-325 hemostatic spray; 58% of lesions were Forrest Ib (oozing) and 19% Forrest Ia (spurting).

Initial hemostasis was achieved in 88% of patients and rebleeding occurred in 17%. All-cause morta…

Reviewing Author

John R. Saltzman, MD

Disclosures

Consultant/Advisory BoardIterative Scopes

Editorial BoardsGastrointestinal Endoscopy; UpToDate

Leadership Positions in Professional SocietiesAmerican College of Gastroenterology (Trustee)

OtherVice President of Medical Affairs, 1Globe Health Institute