Loading...
Patients with primary hyperparathyroidism (PHPT) occasionally present with consistently normal serum calcium even after correction for serum albumin — a variant known as normocalcemic PHPT. In this cross-sectional study from several endocrinology departments in Italy, researchers compared characteristics of 47 patients with normocalcemic PHPT, 41 patients with conventional hypercalcemic PHPT, and 39 control patients (seen for reasons unrelated to parathyroid or bone disorders). Mean age in all three groups was 64, nearly all patients were women, and all patients had normal renal function.
Key findings were as follows:
Mean serum calcium was 9.4 mg/dL in the normocalcemic-PHPT group and 10.8 mg/dL in the hypercalcemic-PHPT group, but mean para…