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Transient elastography (TE) measurement can diagnose fibrosis stage noninvasively in patients with nonalcoholic fatty liver disease (NAFLD). To assess whether it can also predict liver-related outcomes and survival in those with advanced fibrosis, investigators conducted a retrospective study in 1039 patients with NAFLD and stage 3 or 4 fibrosis established by histology or TE measurement (>10 kPa) who were followed for at least 6 months.
TE measurements were taken at baseline, and follow-up TE measurements (available in 533 patients) were taken within 1 year before the last day of study follow-up. Improvement was defined as >20% reduction in TE value from baseline, worsening was defined as >20% increase from baseline, and stability as change…