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Management of splanchnic vein thrombosis (SVT) — which involves portal, hepatic, mesenteric, and splenic veins — is complicated by a lack of high-quality clinical trials to guide treatment. Further, bleeding risk can extend beyond that attributed to anticoagulation, given that patients may have portal hypertension. Here, an international expert panel, on behalf of ISTH, convened to provide practical guidance on managing patients with SVT and focused on the type and duration of anticoagulant treatment.
When acute SVT is complicated by intestinal infarction, peritonitis, shock, lactic acidemia, or major hemorrhage, sur…