EEG: An Early Marker for Dementia with Lewy Bodies?

Electroencephalography may assist in the diagnosis and prognosis of dementia with Lewy bodies at the mild cognitive impairment stage.

Dementia with Lewy bodies (DLB) is clinically associated with dementia plus core clinical features including visual hallucinations, REM sleep behavior disorder, cognitive fluctuations, and parkinsonism. An abnormal electroencephalogram (EEG) is a supportive biomarker for DLB.

To determine whether EEGs can differentiate between DLB and Alzheimer disease (AD) at the mild cognitive impairment (MCI) stage and prognosticate conversion from MCI to DLB, researchers in the Netherlands studied 104 patients (mean age, ~68 years) with MCI from the Amsterdam Dementia Cohort between 2000 and 2017. Of these patients, 37 had developed DLB or had an abnormal SPECT scan or at least one core clinical feature of DLB (MCI-DLB group), and 67 had cerebrospinal fl…

Reviewing Author

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

EEG: An Early Marker for Dementia with Lewy Bodies?

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Reviewing Author