Setting Criteria for Pulmonary Aspergillosis During COVID-19

In a prospective, multicenter cohort trial of intubated patients with COVID-19, 27.7% were identified as having pulmonary aspergillosis using a definition based on influenza.

While invasive pulmonary aspergillosis (PA) is usually seen among patients with highly suppressed immune systems, it has been recently recognized in those with influenza, and now in those with COVID-19. Presentation of PA as a complication of these viral infections appears to be distinct. New diagnostic rules have been developed. These authors, from Bologna, Italy, performed a prospective, multicenter cohort study in Italy from February through April, 2020, among 108 adult patients with COVID-19 who were on mechanical ventilation. All patients underwent bronchoalveolar lavage (BAL) and had serum and BAL Aspergillus galactomannan (GM) levels obtained. Probable PA was defined according to a recently proposed COVID-19–associated PA (CAPA) defi…

Reviewing Author

Neil M. Ampel, MD

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Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Setting Criteria for Pulmonary Aspergillosis During COVID-19

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Reviewing Author