Endovascular Therapy for Ischemic Stroke Very Late After Symptom Onset

Some patients may have slow progression of ischemic stroke and salvageable brain tissue beyond the 16- to 24-hour time window of current guidelines.

Endovascular treatment (EVT) is an established option for selected patients with large-vessel occlusion (LVO) and acute ischemic stroke. EVT was first established for patients who could be treated within 6 hours after stroke onset. Subsequently, trials using advanced imaging demonstrated benefit in selected patients up to 16 or even 24 hours after stroke onset. Whether even later treatment has benefit has not been studied. These authors retrospectively analyzed data from patients who had ischemic stroke and LVO (of the internal carotid or middle cerebral artery) who presented to one center beyond 16 hours. The authors retrospectively assessed infarct core and volume of hypoperfused tissue (i.e., mismatch). A good outcome was defined as 90-d…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Endovascular Therapy for Ischemic Stroke Very Late After Symptom Onset

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Reviewing Author