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The primary approach to diagnosing SARS-CoV-2 infection has become the use of highly sensitive nucleic acid amplification tests (NAATs), despite the fact that these tests are relatively expensive, require sophisticated laboratory technology, and have a turnaround time (TAT) that can extend beyond 10 days in many parts of the U.S. Two new studies now indicate that the use of a less sensitive test that could be performed more frequently would be a better option for preventing the spread of the COVID-19 pandemic.
In the first study, Paltiel and colleagues modeled the cost-efficacy of routine screening using tests with sensitivities varying from 70% to 90%, and performed from once daily to once weekly, to prevent the spread of SARS-CoV-2 among 5…