Acute Kidney Injury After Pediatric Heart Surgery: Risk for Chronic Kidney Disease and Hypertension?

CKD and hypertension each developed in roughly 20% of children 48 months after discharge, but only hypertension was associated with AKI and only in the first year.

Although acute kidney injury (AKI) is common after pediatric heart surgery, the long-term consequences remain unknown. In a prospective study of 124 children ages 1 month to 18 years undergoing heart surgery at two children's hospitals, researchers monitored proteinuria, hypertension, and chronic kidney disease (CKD) 3 months after discharge and annually for 48 months.

Postoperative AKI developed in 46% of patients (only one child was dialyzed). Factors associated with AKI included younger age and higher preoperative estimated glomerular filtration rate (eGFR). The prevalence of CKD (defined as low eGFR or proteinuria) increased from 20% at 3 months to 39% at 12 months and then declined to 17% at 48 months. AKI was not associated with develo…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Acute Kidney Injury After Pediatric Heart Surgery: Risk for Chronic Kidney Disease and Hypertension?

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Reviewing Author