Surveillance Upper Endoscopy: Does Image Enhancement Method Affect Gastrointestinal Neoplasm Yield?

Examination with linked color imaging was superior to white light imaging at detecting early neoplastic lesions.

In endoscopic detection of early neoplastic lesions of the pharynx, esophagus, and stomach, lesions can be difficult to discern and challenging to visualize using white light imaging (WLI). Enhanced imaging methods including narrow band imaging (NBI) and blue laser imaging (BLI) have been utilized to improve diagnostic yield. Now, data are available on linked color imaging (LCI), a novel laser technology that enhances subtle differences in gastrointestinal (GI) mucosal color.

In an industry-funded, prospective, multicenter trial in Japan, patients with previous or current upper GI tract neoplasm undergoing surveillance endoscopy were randomized to undergo initial examination with LCI (n=750) or WLI (n=752) followed by the alternate mode in a…

Reviewing Author

John R. Saltzman, MD

Disclosures

Consultant/Advisory BoardIterative Scopes

Editorial BoardsGastrointestinal Endoscopy; UpToDate

Leadership Positions in Professional SocietiesAmerican College of Gastroenterology (Trustee)

OtherVice President of Medical Affairs, 1Globe Health Institute