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The population-wide effect of a COVID-19 vaccine is determined as much by its acceptance as by its immunologic properties. In this U.S. study, researchers surveyed 1971 adults in July 2020 to determine factors associated with acceptance of a COVID-19 vaccine. Respondents were asked whether they would receive a hypothetical vaccine based on variations in seven categories.
Based on all combinations of the variables, the acceptance rate was 56%. Acceptance was significantly higher with greater efficacy (i.e., 90% vs. 50%), longer duration of protection (i.e., 5 years vs. 1 year), and less-frequent severe adverse effects (i.e., 1 in 1 million vs. 1 in 10,000); acceptance was influenced moderately by frequency of minor adverse effects (i.e., 1 in…