Active Surveillance for Black vs. White Men with Low-Risk Prostate Cancer

Active surveillance is increasingly preferred as standard management for men with low-risk prostate cancer, given its favorable biology and patients' desire to avoid therapy-related adverse effects. However, some data suggest that low-grade prostate cancer in Black patients may exhibit a more aggressive disease biology and make these patients less optimal candidates for active surveillance.

Using data from the U.S. Veterans Health Administration Health Care System, investigators conducted a retrospective cohort study to compare clinical outcomes between 2280 Black men and 6446 non-Hispanic white men diagnosed with low-risk prostate cancer and managed with active surveillance over a 14-year period (2001–2015). Among this group, Black men were…