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This guideline is focused on long-term oxygen therapy (LTOT) for patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease. Recommendations are based on best available evidence and patient-specific risks and benefits.
Patients with COPD and severe resting hypoxemia (partial pressure of oxygen [PaO2], ≤55 mm Hg or oxygen saturation [SpO2], ≤88%) should be prescribed LTOT for at least 15 hours daily.
Patients with COPD and severe exertional desaturation should be prescribed ambulatory oxygen.
Patients with interstitial lung disease should receive LTOT for severe resting hypoxemia and ambulatory oxygen for severe exertional desaturation. The…