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Thrombosis occurs frequently in hospitalized patients with COVID-19. Although guidelines recommend pharmacologic prophylaxis for patients hospitalized with COVID-19, practices vary in dosing. In two reports, researchers addressed pharmacologic dosing strategies for thromboembolism prophylaxis in hospitalized COVID-19 patients.
In a meta-analysis, authors pooled data from 35 cohort studies to compare pharmacologic dosing strategies among nearly 11,000 hospitalized COVID-19 patients. Pooled incidence of venous thromboembolism (VTE) and arterial thromboembolism was significantly lower in patients who received any pharmacologic prophylaxis, but the various dosing strategies did not yield significant differences in outcomes (see ).
In a retro…